Wuhan Yuancheng Gongchuang Tech Co.,Ltd
Wuhan Yuancheng Gongchuang Tech Co.,Ltd,a big leading supplier of chemical material
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High Quality Pharmaceutical Chemical CAS 4759-48-2 Isotretinoin
| Product Name | Isotretinoin (Roaccutane),Accutane |
| Synonyms | 13-cis retinoic acid ;Isoretinoin;isotrex;neovitaminaacid;roaccutane;teriosal;Lsotretinoin |
| CAS No. | 4759-48-2 |
| EINECS No. | 225-296-0 |
| Molecular Formula | C20H28O2 |
| Molecular Weight | 300.44 |
| Melting point | 172-175 °C |
| Appearance | orange red crystal |
| Grade | Pharmaceutical grade |
| Application | drug for skin use |
Isotretinoin,also known as 13-cis retinoic acid and first marketed as Accutane by Hoffmann-La Roche, is an oral pharmaceutical drug primarily used to treat cystic acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tretinoin, is also an acne drug.
Isotretinoin is primarily used as a treatment for severe acne. The most common adverse effects are a transient worsening of acne (lasting 2-3 weeks), dry lips (cheilitis), dry and fragile skin, and an increased susceptibility to sunburn. Uncommon and rare side effects include: muscle aches and pains (myalgias), and headaches. Isotretinoin is known to cause birth defects due to in utero exposure because of the molecule's close resemblance to retinoic acid, a natural vitamin A derivative which controls normal embryonic development.
In the United States a special procedure is required to obtain the pharmaceutical. In most other countries a consent form is required which explains these risks. Women taking isotretinoin must not get pregnant during, and for 1 month after isotretinoin therapy. Sexual abstinence, or effective contraception is mandatory during this period. Barrier methods by themselves (such as condoms) are not considered adequate due to the unacceptable failure rates of approximately 3%. Women who fall pregnant whilst on isotretinoin therapy are generally counselled to have a termination. Isotretinoin has no effect on male reproduction.
Isotretinoin is used primarily for severe cystic acne and acne that has not responded to other treatments.Acne treatment usually begins with topical retinoids ,in combination with topical antibiotics or antiseptics , followed by oral antibiotics .In women a cyproterone acetate-containing contraceptive pill can be useful if there are no contraindications.
In cases of hormonal acne, such as in women in their 20s and 30s with cyclical acne, often a course of isotretinoin can permanently improve acne obviating the need for lifelong hormonal manipulation.
Company Profile
Hubei Yuancheng Gongchuang Technology Co. Ltd,is a bio company founded in 2001 in Wuhan.Our main products include veterinary drugs,anaimal extracts,paint,vitamin and amino acid,food additives,feed additives,essence,which are widely used in medicines,food,beverage,cosmetics,food supplements,heath products and so on.Our company enjoys a reputation in China for its high standards of quality chemical paroducts,low price and pleasant service.Yuancheng's business is based on trustworthiness and persistence.I really hope to establish a cordial coperation relationship with you and let's create a win-win situation!
Covered with an area of 33500 square meters,the factory is located in Xiaogan city,about the 107 national road,marched with Wuhan.With clean environment and nice layout,there are several large-sized,medium-sized workshops and QA and research center with advanced equipment.We invests large fund and brains to R&D department to research fine chermical,biochemical,pharmaceutical that fit the demand of the market.High level research group,advanced appatatus and good scientific atmosphere ensure the quality of R&D.Our products reach the advanced standard of domestic market,many of which reach the international standard.
Technique support is available whenever you have questions in making our products into finished products or when using.With over 14 years'experience exporting our products worldwide,we have a high customs pass rate ,also package will be free resent to you in case it get sized."Delivery guarantee,Quality service"is our promise for you!
High quality,competitive price,fast delivery,best package,safe shipping and reship policy service gain the trust and praise from the customers all over the world.Let's join hand,go further and win together!
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Hubei Yuancheng Gongchuang Technology Co.Ltd,is a leading Chinese chemical supplier specialized in our products.We strive to maintain and improve every phase of our business and satisfy needs of our customers.All products at our site are available to be shipped,that means we have them in stock and can ship them to you within 48 hours after payment clearance.With over 13 years experience online we offer a 100% delivery guarantee.If your parcels do not arrive in time we will reship.You will make sure that customer satisfaction and assurance is priority number one.Also discounts are available for our second-time customers.
Our company's various raw chemical material materials are of reliable quality,most of which conform to the requirement of FCC,USP,and BP,it is mainly sold to pharmacy companies and heath care companies abroad.Our target markets comrise of USA,Canada,UK,Brazil,Netherlands,Ireland,New zealand,Australia,Austria,and so on.Due to over 10 years of experience in this industriy,our absolute advantage is reflected in our mature manufacturing management system,quality assurance system and sales service system.
History
Hubei Yuancheng Gongchuang Technology Co. Ltd is founded in 2003.The founder Mr.Ye Chuanfa pours a huge amount of money for the products.And there are more than 200 technical staffs participating in R&D during these years,and we are constantly making revolutionary breakthoughs.Our main products are cinnamic aldehyde,cinnamic acid,cinnamic alcohol,ect.They are widely used in pharmaceuticals,food additives,flavors and fragrances,cosmetics,agriculture,forestry,rubber,plastics,electroplating,oil exploration and other fields,and its derivatives are rapidly extending to the LCD,aerospace,poteoelectronics and other cutting-edge fields,which are qualified by several word-famous flavor and pharmaceutical companies.Our company achieve million of US dollars of sales revenue in recent years.We conducted more than 50 kinds of scientific research,and enjoy more than 20 national patents.We have even acquired 5 national invention patent certificates,184 products of us are almost unique around the world.
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